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dc.contributor.authorHaro Martínez, Ana
dc.contributor.authorLubrini, Genny
dc.contributor.authorMadero Jarabo, Rosario
dc.contributor.authorDíez Tejedor, Exuperio
dc.contributor.authorFuentes, Blanca
dc.date.accessioned2018-10-15T11:01:37Z
dc.date.available2018-10-15T11:01:37Z
dc.date.issued2018
dc.identifier.issn1477-0873spa
dc.identifier.urihttp://hdl.handle.net/10641/1508
dc.description.abstractObjective: To collect data to estimate the sample size of a definitive randomised clinical trial to evaluate the effects of Melodic Intonation Therapy in poststroke nonfluent aphasia. Design: A randomised, crossover, interventional pilot trial. Setting: Departments of Neurology and Rehabilitation from a university general hospital. Participants: Stroke survivors with poststroke nonfluent aphasia. Interventions: Patients randomised to group 1 had treatment with Melodic Intonation Therapy first (12 sessions over 6 weeks) followed by no treatment; the patients in group 2 started active treatment between 3 and 6 months after their inclusion in the study, serving as waiting list controls for the first phase. Main measures: The Communicative Activity Log (CAL) questionnaire and the Boston Diagnostic Aphasia Examination (BDAE) were evaluated at baseline, and at 6 and 12 weeks. Results: Twenty patients were included. Four of the patients allocated to group 2 crossed over to group 1, receiving the treatment at first. Intention-to-treat analysis: after adjustment for baseline scores, the mean difference in the CAL evaluation from baseline in the treated group was 8.5 points (95% CI, 0.11–17.0; P=.043), with no significant change in any of the BDAE sections. Per protocol analysis showed similar results with a clear treatment effect (P=.043) on the CAL. Conclusions: Melodic Intonation Therapy might have a positive effect on the communication skills of stroke survivors with nonfluent aphasia as measured by the CAL questionnaire. A full-scale trial with at least 27 patients per group is necessary to confirm these results.spa
dc.language.isoengspa
dc.publisherClinical rehabilitationspa
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 España*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/*
dc.subjectIschaemic strokespa
dc.subjectAphasiaspa
dc.subjectMelodic intonation therapyspa
dc.titleMelodic intonation therapy in post-stroke nonfluent aphasia: a randomized pilot trial.spa
dc.typearticlespa
dc.description.versionpre-printspa
dc.rights.accessRightsopenAccessspa
dc.description.extent490 KBspa


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