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dc.contributor.authorMueller, Silke M.
dc.contributor.authorGarcía Arias, María
dc.contributor.authorMejuto Vázquez, Gema
dc.contributor.authorSchiebenera, Johannes
dc.contributor.authorBrand, Matthias
dc.contributor.authorWegmanna, Elisa
dc.date.accessioned2019-04-09T11:02:18Z
dc.date.available2019-04-09T11:02:18Z
dc.date.issued2019
dc.identifier.issn1380-3395spa
dc.identifier.urihttp://hdl.handle.net/10641/1613
dc.description.abstractIntroduction: Making advantageous decisions is a key competence of individuals of all ages. However, previous studies reported a reduction of this competence in patients with neurodegenerative diseases such as Alzheimer’s disease, which is explained by impairments of executive functions such as cognitive flexibility or working memory. While previous findings from healthy participants with reduced executive functions showed that support can improve decision making under risk, the study at hand aimed to investigate this effect in patients with mild Alzheimer’s disease (mAD). Method: A group of elderly individuals diagnosed with mAD (n = 14; mean Mini-Mental State Examination, MMSE = 24.14, SD = 3.18) and a group of healthy age-matched controls (n = 14; mean MMSE = 29.29, SD = 1.98) performed the Game of Dice Task (GDT) three times (t0, t1, t2) with intervals of five to nine days between each: The standard GDT plus other neurocognitive tasks (t0), the GDT with decision support (t1), and again the standard GDT (t2). Results: At any time, mAD patients made more disadvantageous decisions than controls. However, the decision-making performance of mAD patients improved significantly with decision support. Interestingly, when the standard GDT was played again (t2), mAD patients’ performance remained similar to the performance in the GDT with decision support (t1). GDT performance correlated consistently with executive function measures in the control group, but only at t0 in the mAD group. Conclusions: The findings indicate that supportive information about the riskiness of options can compensate for mAD-related deficits in decision making under risk. Thus, decision support can improve the quality of mAD patients’ decisions. Further, it may prevent mAD patients from making highly risky decisions in similar situations in the future. The persistence of decision support should be further investigated as it has relevant implications for everyday decisions that include risks.spa
dc.language.isoengspa
dc.publisherJournal of Clinical and Experimental Neuropsychologyspa
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 España*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/*
dc.subjectAlzheimer’s diseasespa
dc.subjectDecision makingspa
dc.subjectDecision supportspa
dc.subjectExecutive functionsspa
dc.subjectGame of Dice Taskspa
dc.titleDecision Support in Patients with mild Alzheimer’s Disease.spa
dc.typearticlespa
dc.description.versionpre-printspa
dc.rights.accessRightsopenAccessspa
dc.description.extent577 KBspa
dc.identifier.doi10.1080/13803395.2019.1585517spa


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