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dc.contributor.authorBarbado, David
dc.contributor.authorGómez Illán, Ramón
dc.contributor.authorMoreno Navarro, Pedro
dc.contributor.authorMendoza Laiz, Nuria
dc.contributor.authorReina Vaillo, Raúl
dc.contributor.authorSempere, Ángel P.
dc.date.accessioned2019-11-04T12:23:21Z
dc.date.available2019-11-04T12:23:21Z
dc.date.issued2018
dc.identifier.issn0214-0071spa
dc.identifier.urihttp://hdl.handle.net10641/1714
dc.description.abstractAlthough the advance in disease-modifying drugs has helped to stabilize the multiple sclerosis (MS) course increasing life-expectancy, physical deterioration still supervenes over time in most MS patients. In this context, physical exercise programs are considered a safe and well-tolerated tool to preserve functional independence in this population, which not only provides similar fitness improvements as usually observed in healthy general population, but it may also ameliorate some of the symptoms that this pathology entails (as fatigue, balance deficits, muscle weakness, etc.). Nowadays, the question is if exercise only aids to reverse physical deconditioning associated to the disease or it has the potential to have an impact on MS progression. In the present overview, the role of exercise as complementary therapy for modulating various physiopathological pathways related to MS disease such as inflammation and the neurotrophic support for neuronal survival was revised. Specifically, the exercise ability to modulate the immune system behaviour regulating the pro- and anti-inflammatory cytokine balance, as well as, to promote neuroprotective and neurorestorative mechanisms through the brain-derived neurotrophic factor stimulation was analysed.spa
dc.language.isoengspa
dc.publisherEuropean Journal of Human Movementspa
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 España*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/*
dc.subjectMultiple sclerosisspa
dc.subjectExercisespa
dc.subjectCytokinesspa
dc.subjectBrain-derived neurotrophic factorspa
dc.subjectBrain atrophyspa
dc.titleDoes exercise have a neuroprotective function in multiple sclerosis? A brief overview of the physical training potential effects on cytokines and brain-derived neurotrophic factor.spa
dc.typearticlespa
dc.description.versionpost-printspa
dc.rights.accessRightsopenAccessspa
dc.description.extent304 Bspa
dc.relation.publisherversionhttps://www.eurjhm.com/index.php/eurjhm/article/view/473spa


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Except where otherwise noted, this item's license is described as Atribución-NoComercial-SinDerivadas 3.0 España