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dc.contributor.authorMartínez Relimpio, Ana María 
dc.contributor.authorBenito, Marta
dc.contributor.authorPérez, Elena
dc.contributor.authorTeijón, José María
dc.contributor.authorBlanco, María Dolores
dc.date.accessioned2019-11-18T08:49:49Z
dc.date.available2019-11-18T08:49:49Z
dc.date.issued2016
dc.identifier.issn1381-6128spa
dc.identifier.urihttp://hdl.handle.net10641/1742
dc.description.abstractCancer has become one of the main causes of death in developed countries, and it is expected to be declared as the disease with the highest worldwide morbidity and mortality indexes in the coming decades. Nanomedicine aims to overcome some problems related to this prevalent disease, particularly the lack of efficient diagnostic and therapeutic tools. The most recent scientific advances, which have conducted to a more personalized medicine, were focused on the production of nanocarriers involved into the transport and the delivery of drugs to targeted cells. A wide variety of nanocarriers composed by different materials have been designed for their use as drug delivery systems. Polysaccharides have emerged as very useful biopolymers among all raw materials used in the preparation of these nanoplatforms. They are highly stable, non-toxic and biodegradable molecules, and also present some chemical properties which are very difficult to reproduce using artificial polymers. Anionic polymers, such as hyaluronic acid, heparin or alginate, present some structural and chemical characteristics which make them ideal polymers to prepare nanosystems with anticancer applications. This review will focus on the description of some anionic polysaccharides and the possibilities they offer towards the preparation of nanosystems with applications in cancer treatment and diagnostics.spa
dc.language.isoengspa
dc.publisherCurrent Pharmaceutical Designspa
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 España*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/*
dc.subjectCancerspa
dc.subjectNanomedicinespa
dc.subjectNatural polymersspa
dc.subjectAnionic polysaccharidesspa
dc.subjectDrug deliveryspa
dc.subjectNanocarriersspa
dc.titleThe role of anionic polysaccharides in the preparation of nanomedicines with anticancer applications.spa
dc.typearticlespa
dc.description.versionpre-printspa
dc.rights.accessRightsopenAccessspa
dc.description.extent889 KBspa
dc.identifier.doi10.2174/1381612822666160128145125spa
dc.relation.publisherversionhttp://www.eurekaselect.com/138867/articlespa


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Except where otherwise noted, this item's license is described as Atribución-NoComercial-SinDerivadas 3.0 España