Show simple item record

dc.contributor.authorGarcía-Serrano, Alba
dc.contributor.authorTomé-Carneiro, Joao
dc.contributor.authorCrespo, M. Carmen
dc.contributor.authorVisitación Calvo, M.
dc.contributor.authorPereda Pérez, Inmaculada
dc.contributor.authorBaliyan, Shishir
dc.contributor.authorBurgos-Ramos, Emma
dc.contributor.authorMontero, Olimpio
dc.contributor.authorDávalos, Alberto
dc.contributor.authorVenero, César
dc.contributor.authorVisioli, Francesco
dc.contributor.authorFontecha, Javier
dc.date.accessioned2020-05-07T12:00:39Z
dc.date.available2020-05-07T12:00:39Z
dc.date.issued2020
dc.identifier.issn0952-3278spa
dc.identifier.urihttp://hdl.handle.net/10641/1909
dc.description.abstractCognitive decline is one of the hallmarks of aging and can vary from mild cognitive impairment to dementia to Alzheimer's disease. In addition to some lifestyle interventions, there is room for the use of nutraceuticals/functional foods as pharma-nutritional tools to lessen the burden of cognitive decline before it worsens. We previously reported the promising molecular actions of milk fat globule membranes and krill oil concentrates in a rat model of aging. In this study, we concentrated on the activities on cognition, using an array of validated tests. We also performed lipidomic analyses of plasma, erythrocytes, and different brain areas. We report lower emotional memory (contextual fear conditioning) in aged rats supplemented with concentrates of polar lipids from buttermilk or krill oil at doses that approximate human consumption. No other behavioral parameter was significantly influenced by the supplements, calling for further research to confirm or not the purported salubrious activities of polar lipids, namely those rich in ω3 long-chain polyunsaturated fatty acids, on cognitive decline.spa
dc.language.isoengspa
dc.publisherProstaglandins, Leukotrienes and Essential Fatty Acidsspa
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 España*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/*
dc.subjectAgingspa
dc.subjectBehaviorspa
dc.subjectCognitive declinespa
dc.subjectFunctional foodsspa
dc.subjectNutraceuticalsspa
dc.subjectOmega 3 fatty acidsspa
dc.subjectPhospholipidsspa
dc.titleConcentrates of buttermilk and krill oil improve cognition in aged ratsspa
dc.typearticlespa
dc.description.versionpre-printspa
dc.rights.accessRightsopenAccessspa
dc.description.extent1609 KBspa
dc.identifier.doi10.1016/j.plefa.2020.102077spa
dc.relation.publisherversionhttps://www.plefa.com/article/S0952-3278(20)30035-1/pdfspa


Files in this item

FilesSizeFormatView
1.- Concentrates of buttermilk.pdf1.571MbPDFView/Open

This item appears in the following Collection(s)

Show simple item record

Atribución-NoComercial-SinDerivadas 3.0 España
Except where otherwise noted, this item's license is described as Atribución-NoComercial-SinDerivadas 3.0 España