dc.contributor.author | Cristóbal García, Ignacio | |
dc.contributor.author | Lorite Aguilera, Lidia | |
dc.contributor.author | Álvarez Martinez, Esperanza | |
dc.contributor.author | Piedrabuena, Verónica | |
dc.date.accessioned | 2020-10-07T10:36:09Z | |
dc.date.available | 2020-10-07T10:36:09Z | |
dc.date.issued | 2019 | |
dc.identifier.issn | 0304-5013 | spa |
dc.identifier.uri | http://hdl.handle.net/10641/1993 | |
dc.description.abstract | Objective: To describe the clinical progress of women with vaginal atrophy who receive nonhormonal treatment.
Material and methods: Single-center retrospective longitudinal observational descriptive study in postmenopausal women aged 45-60 years with symptoms of vaginal atrophy who required nonhormonal treatment.
Results: We included 98 women with a mean (SD) age of 54.6 (3.2) years and a mean time of 5.6 (3.0) years without menstrual periods. Of these, 63.3% were treated with hyaluronic acid and Centella asiatica cell lysate and the other 36.7% with glycerin and polycarbophil. The vaginal maturation index improved significantly after 3 months of treatment with hyaluronic acid and Centella asiatica: the parabasal cell count declined (-8.4%; 95%CI, –10.6 to –6.2; p=0.001) and the intermediate cell count increased (3.6%; 95%CI, 2.0-5.3; p=0.001), as did that of superficial cells (4.8%; 95%CI, 3.8-5.7; p=0.001). In addition, all symptoms and signs of vaginal atrophy improved after 3 months with treatment with hyaluronic acid and Centella asiatica lysate. There was no significant change in the vaginal maturation index or in symptoms and signs after 3 months of treatment with glycerin and polycarbophil.
Conclusions: Three months of nonhormonal treatment with hyaluronic acid and Centella asiatica lysate significantly improved the vaginal maturation index. | spa |
dc.language.iso | eng | spa |
dc.publisher | Progresos de obstetricia y ginecología. | spa |
dc.rights | Atribución-NoComercial-SinDerivadas 3.0 España | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | * |
dc.subject | Vaginal atrophy | spa |
dc.subject | Treatment | spa |
dc.subject | Menopause | spa |
dc.subject | Hyaluronic acid | spa |
dc.subject | Vaginal maduration index | spa |
dc.title | Effectiveness of nonhormonal products for the treatment of women with vaginal atrophy. [Efectividad de productos no hormonales para el tratamiento de las mujeres con atrofia vaginal]. | spa |
dc.type | journal article | spa |
dc.type.hasVersion | AM | spa |
dc.rights.accessRights | open access | spa |
dc.description.extent | 346 KB | spa |
dc.identifier.doi | 10.20960/j.pog.00196 | spa |
dc.relation.publisherversion | https://sego.es/Listado_de_Numeros | spa |