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dc.contributor.authorWitteles, Ronald M.
dc.contributor.authorBokhari, Sabahat
dc.contributor.authorDamy, Thibaud
dc.contributor.authorElliott, Perry M.
dc.contributor.authorFalk, Rodney H.
dc.contributor.authorFine, Nowell M.
dc.contributor.authorGospodinova, Mariana
dc.contributor.authorObici, Laura
dc.contributor.authorRapezzi, Claudio
dc.contributor.authorGarcía Pavía, Pablo 
dc.date.accessioned2020-10-13T14:45:35Z
dc.date.available2020-10-13T14:45:35Z
dc.date.issued2019
dc.identifier.issn2213-1779spa
dc.identifier.urihttp://hdl.handle.net/10641/2002
dc.description.abstractTransthyretin amyloid cardiomyopathy (ATTR-CM) is a life-threatening, progressive, infiltrative disease caused by the deposition of transthyretin amyloid fibrils in the heart, and can often be overlooked as a common cause of heart failure. Delayed diagnosis due to lack of disease awareness and misdiagnosis results in a poorer prognosis. Early accurate diagnosis is therefore key to improving patient outcomes, particularly in the context of both the recent approval of tafamidis in some countries (including the United States) for the treatment of ATTR-CM, and of other promising therapies under development. With the availability of scintigraphy as an inexpensive, noninvasive diagnostic tool, the rationale to screen for ATTR-CM in high-risk populations of patients is increasingly warranted. Here the authors propose a framework of clinical scenarios in which screening for ATTR-CM is recommended, as well as diagnostic “red flags” that can assist in its diagnosis among the wider population of patients with heart failure.spa
dc.language.isoengspa
dc.publisherJACC: Heart Failurespa
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 España*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/*
dc.subjectAmyloidosisspa
dc.subjectCardiomyopathyspa
dc.subjectDiagnosisspa
dc.subjectTransthyretin amyloidspa
dc.titleScreening for Transthyretin Amyloid Cardiomyopathy in Everyday Practice.spa
dc.typejournal articlespa
dc.type.hasVersionAMspa
dc.rights.accessRightsopen accessspa
dc.description.extent587 KBspa
dc.identifier.doihttps://doi.org/10.1016/j.jchf.2019.04.010spa
dc.relation.publisherversionhttps://heartfailure.onlinejacc.org/content/7/8/709spa


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Except where otherwise noted, this item's license is described as Atribución-NoComercial-SinDerivadas 3.0 España