Capnometry levels as an indicator of renal graft evolution in uncontrolled non-heart beating donors: [Niveles de capnometría como indicador de evolución de injerto renal de donantes en asistolia no controlada].
Author: Mateos Rodríguez, Alonso; Varillas Delgado, David; Villar Arias, A.; Rubio Chacón, C.; Andrés Belmonte, A.
Abstract: Objective: The capnometry values during resuscitation are an evolutive predictor of kidneys obtained from uncontrolled non-heart beating donors.
Design: The study comprised a retrospective onset cohort of 37 non-heart beating donors and a validation cohort of 55 transplanted kidneys in the period 2013–2017.
Scope: The population served by the emergency service and referred to Hospital Universitario Doce de Octubre (Madrid, Spain) as potential uncontrolled non-heart beating donors.
Patients: A total of 55 renal transplant patients subjected to hemodialysis and with grafts from uncontrolled non-heart beating donors.
Interventions: Capnometry and capnography measurements in potential uncontrolled non-heart beating donors.
Variables: Capnometry values recorded initially and at transfer in hospital for comparison with the viability of the extracted kidneys; renal failure and delayed renal function.
Results: A total of 55 out of 74 extracted kidneys were transplanted (74.3%). The rest were ruled out due to poor perfusion or signs of ischemia. An association was observed (p = 0.016) between the capnometry values during resuscitation in the grafted kidneys (µ = 22.8 mmHg) and in the kidneys discarded for transplantation (µ = 17.35 mmHg).
Conclusions: Capnometry during resuscitation serves as a marker to be taken into account in relation to the viability of the transplanted organs in uncontrolled non-heart beating donors.
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