Show simple item record

dc.contributor.authorGutiérrez Hellín, Jorge 
dc.contributor.authorBaltazar Martins, Gabriel
dc.contributor.authorAguilar Navarro, Millán 
dc.contributor.authorOliván, Jesús
dc.contributor.authorDel Coso, Juan
dc.description.abstractThe p.R577X polymorphism (rs1815739) in the ACTN3 gene causes individuals with the ACTN3 XX genotype to be deficient in functional α-actinin-3. Previous investigations have found that XX athletes are more prone to suffer non-contact muscle injuries. This investigation aimed to determine the influence of the ACTN3 R577X polymorphism in the injury epidemiology of elite endurance athletes. Using a cross-sectional experiment, the epidemiology of running-related injuries was recorded for one season in a group of 89 Spanish elite endurance runners. ACTN3 R577X genotype was obtained for each athlete using genomic DNA samples. From the study sample, 42.7% of athletes had the RR genotype, 39.3% had the RX genotype, and 18.0% had the XX genotype. A total of 96 injuries were recorded in 57 athletes. Injury incidence was higher in RR runners (3.2 injuries/1000 h of running) than in RX (2.0 injuries/1000 h) and XX (2.2 injuries/1000 h; p = 0.030) runners. RR runners had a higher proportion of injuries located in the Achilles tendon, RX runners had a higher proportion of injuries located in the knee, and XX runners had a higher proportion of injuries located in the groin (p = 0.025). The ACTN3 genotype did not affect the mode of onset, the severity, or the type of injury. The ACTN3 genotype slightly affected the injury epidemiology of elite endurance athletes with a higher injury rate in RR athletes and differences in injury location. However, elite ACTN3 XX endurance runners were not more prone to muscle-type
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 España*
dc.subjectAthletic performancespa
dc.subjectExercise-related injuryspa
dc.subjectSingle nucleotide polymorphismspa
dc.subjectTrack and field athletespa
dc.titleEffect of ACTN3 R577X Genotype on Injury Epidemiology in Elite Endurance Runners´.spa
dc.description.extent248 KBspa

Files in this item

1.- Effect of ACTN3 R577X ...247.6KbPDFView/Open

This item appears in the following Collection(s)

Show simple item record

Atribución-NoComercial-SinDerivadas 3.0 España
Except where otherwise noted, this item's license is described as Atribución-NoComercial-SinDerivadas 3.0 España