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What does not kill you makes you stronger: surviving anti-cancer therapies by cytoskeletal remodeling and Myosin II reactivation.

dc.contributor.authorOrgaz, José L.
dc.contributor.authorSanz Moreno, Victoria
dc.date.accessioned2021-04-23T10:59:55Z
dc.date.available2021-04-23T10:59:55Z
dc.date.issued2020
dc.identifier.issn2372-3556spa
dc.identifier.urihttp://hdl.handle.net/10641/2302
dc.description.abstractMyosin II and its regulator Rho-associated coiled-coil containing protein kinase (ROCK) are essential for cell invasion and metastatic dissemination. Our recent findings show that this molecular machinery is also involved in drug resistance in melanoma by playing a dual role: protection of tumor cells from reactive oxygen species (ROS) and DNA damage (intrinsic), and co-option of myeloid and lymphoid populations to establish immunosuppression (extrinsic).spa
dc.language.isoengspa
dc.publisherMolecular & Cellular Oncologyspa
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 España*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/*
dc.subjectMyosin IIspa
dc.subjectCytoskeletal remodelingspa
dc.subjectMelanoma therapy resistancespa
dc.subjectTranscriptional rewiringspa
dc.subjectImmunotherapyspa
dc.titleWhat does not kill you makes you stronger: surviving anti-cancer therapies by cytoskeletal remodeling and Myosin II reactivation.spa
dc.typejournal articlespa
dc.type.hasVersionAMspa
dc.rights.accessRightsopen accessspa
dc.description.extent1758 KBspa
dc.identifier.doi10.1080/23723556.2020.1735911spa
dc.relation.publisherversionhttps://www.tandfonline.com/doi/full/10.1080/23723556.2020.1735911spa


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