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dc.contributor.authorUdina-Cortés, Carlos
dc.contributor.authorFernández-Carnero, Josué
dc.contributor.authorArribas Romano, Alberto
dc.contributor.authorCuenca Zaldívar , Juan Nicolás 
dc.contributor.authorVillafañe, Jorge Hugo
dc.contributor.authorCastro-Marrero, Jesús
dc.contributor.authorAlguacil-Diego, Isabel María
dc.date.accessioned2021-10-28T08:31:42Z
dc.date.available2021-10-28T08:31:42Z
dc.date.issued2020
dc.identifier.issn0025-7974spa
dc.identifier.urihttp://hdl.handle.net/10641/2530
dc.description.abstractBackground: To evaluate the effectiveness of non-invasive neuro-adaptive electrostimulation (NAE) therapy for treating chronic pain and disability in patients with fibromyalgia. Method/design: A prospective, randomized, sham-controlled study was conducted in 37 women with fibromyalgia. Participants were randomly assigned to receive either active NAE (n = 20) or stimulation with a sham device (n = 17). Participants in the experimental arm received eight 30-minute sessions over 4 weeks (2 sessions per week). The sham group received eight 30-minute sessions of sham stimulation. Therapeutic effects on pain relief, disability, and quality of life were evaluated using outcome measures at baseline, at 4 weeks, and after 3 months’ follow-up. Results: The findings indicated a significant reduction of pain in the active NAE group compared with the sham group immediately post-intervention, with a difference on the Visual Analog Scale (VAS) of 3 points (P = .001), and at 3 months’ follow-up (P = .02). There were significant intragroup differences between the groups (P < .05) at post-intervention. After the intervention, both groups presented significant reductions on the Fibromyalgia Impact Questionnaire (FIQ) with respect to baseline (P = .004), but not at the 3-month follow-up. In the conditioned pain modulation (CPM) in thumb variable we found significant differences between the groups at the 3-month follow-up (P = .02). No additional benefits for conditioned pain modulation and disability were observed between groups at the 3-month follow-up. Furthermore, anxiety/depression and catastrophizing improved in both groups, but no differences between groups were found. Conclusions: In this fibromyalgia cohort, NAE therapy significantly improved pain and quality of life at 4 weeks, but not at 3-month follow-up, compared with the sham stimulation group. Future investigations are needed in larger populations to confirm these findings.spa
dc.language.isoengspa
dc.publisherMedicinespa
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 España*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/*
dc.subjectelectrostimulationspa
dc.subjectfibromyalgiaspa
dc.subjectpainspa
dc.subjectrehabilitationspa
dc.titleEffects of neuro-adaptive electrostimulation therapy on pain and disability in fibromyalgia A prospective, randomized, double-blind study.spa
dc.typearticlespa
dc.description.versionpost-printspa
dc.rights.accessRightsopenAccessspa
dc.description.extent364 KBspa
dc.identifier.doi10.1097/MD.0000000000023785spa
dc.relation.publisherversionhttps://journals.lww.com/md-journal/Fulltext/2020/12180/Effects_of_neuro_adaptive_electrostimulation.96.aspxspa


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