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dc.contributor.authorTredera, Matthias S.
dc.contributor.authorCharest, Ian
dc.contributor.authorMichelmann, Sebastian
dc.contributor.authorMartín-Buro, María Carmen
dc.contributor.authorRoux, Frederic
dc.contributor.authorCarceller-Benito, Fernando
dc.contributor.authorUgalde-Canitrot, Arturo
dc.contributor.authorRollings, David T.
dc.contributor.authorSawlani, Vijay
dc.contributor.authorChelvarajah, Ramesh
dc.contributor.authorWimber, Maria
dc.contributor.authorHanslmayr, Simon
dc.contributor.authorStaresina, Bernhard P.
dc.date.accessioned2022-03-04T12:27:58Z
dc.date.available2022-03-04T12:27:58Z
dc.date.issued2021
dc.identifier.issn0027-8424spa
dc.identifier.urihttp://hdl.handle.net/10641/2886
dc.description.abstractAdaptive memory recall requires a rapid and flexible switch from external perceptual reminders to internal mnemonic representations. However, owing to the limited temporal or spatial resolution of brain imaging modalities used in isolation, the hippocampal–cortical dynamics supporting this process remain unknown. We thus employed an object-scene cued recall paradigm across two studies, including intracranial electroencephalography (iEEG) and high-density scalp EEG. First, a sustained increase in hippocampal high gamma power (55 to 110 Hz) emerged 500 ms after cue onset and distinguished successful vs. unsuccessful recall. This increase in gamma power for successful recall was followed by a decrease in hippocampal alpha power (8 to 12 Hz). Intriguingly, the hippocampal gamma power increase marked the moment at which extrahippocampal activation patterns shifted from perceptual cue toward mnemonic target representations. In parallel, source-localized EEG alpha power revealed that the recall signal progresses from hippocampus to posterior parietal cortex and then to medial prefrontal cortex. Together, these results identify the hippocampus as the switchboard between perception and memory and elucidate the ensuing hippocampal–cortical dynamics supporting the recall process.spa
dc.language.isoengspa
dc.publisherProceedings of the National Academy of Sciences (PNAS)spa
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 España*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/*
dc.titleThe hippocampus as the switchboard between perception and memory.spa
dc.typearticlespa
dc.description.versionpost-printspa
dc.rights.accessRightsopenAccessspa
dc.description.extent1844 KBspa
dc.identifier.doi10.1073/pnas.2114171118spa
dc.relation.publisherversionhttps://www.pnas.org/doi/10.1073/pnas.2114171118spa


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Atribución-NoComercial-SinDerivadas 3.0 España
Except where otherwise noted, this item's license is described as Atribución-NoComercial-SinDerivadas 3.0 España