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dc.contributor.authorGutiérrez Hellín, Jorge 
dc.contributor.authorAguilar Navarro, Millán 
dc.contributor.authorRuiz Moreno, Carlos
dc.contributor.authorMuñoz Moreno, Alejandro 
dc.contributor.authorAmaro-Gahete, Francisco J.
dc.contributor.authorLópez Samanés, Álvaro 
dc.contributor.authorPosada Ayala, María
dc.contributor.authorDel Coso, Juan
dc.contributor.authorVarillas Delgado, David
dc.description.abstractp-Synephrine is the principal alkaloid of bitter orange (Citrus aurantium). Several recent investigations have found that the intake of 2–3 mg/kg of p-synephrine raises fat oxidation rate during exercise of low-to-moderate intensity. However, these investigations have been carried out only with samples of male participants or mixed men/women samples. Therefore, the aim of this investigation was to study the effect of p-synephrine intake on fat oxidation during exercise of increasing intensity in healthy women. Using a double-blind, randomized experiment, 18 healthy recreationally active women performed two identical exercise trials after the ingestion of (a) 3 mg/kg of psynephrine and (b) 3 mg/kg of a placebo (cellulose). The exercise trials consisted of a ramp test (from 30 to 80% of maximal oxygen uptake; VO2max) on a cycle ergometer while substrate oxidation rates were measured at each workload by indirect calorimetry. In comparison to the placebo, the intake of p-synephrine increased resting tympanic temperature (36.1 ± 0.5 vs. 36.4 ± 0.4 °C p = 0.033, d = 0.87) with no effect on resting heart rate (p = 0.111) and systolic (p = 0.994) and diastolic blood pressure (p = 0.751). During exercise, there was no significant effect of p-synephrine on fat oxidation rate (F = 0.517; p = 0.484), carbohydrate oxidation rate (F = 0.730; p = 0.795), energy expenditure rate (F = 0.480; p = 0.833), heart rate (F = 4.269; p = 0.068) and participant’s perceived exertion (F = 0.337; p = 0.580). The maximal rate of fat oxidation with placebo was 0.26 ± 0.10 g/min and it was similar with p-synephrine (0.28 ± 0.08 g/min, p = 0.449, d = 0.21). An acute intake of 3 mg/kg of p-synephrine before exercise did not modify energy expenditure and substrate oxidation during submaximal aerobic exercise in healthy active women. It is likely that the increase in resting tympanic temperature induced by p-synephrine hindered the effect of this substance on fat utilization during exercise in healthy active
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 España*
dc.subjectSports nutritionspa
dc.subjectWeight lossspa
dc.subjectEndurance exercisespa
dc.subjectWomen athletesspa
dc.titleEffect of p-Synephrine on Fat Oxidation Rate during Exercise of Increasing Intensity in Healthy Active
dc.description.extent519 KBspa

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