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dc.contributor.authorGonzález Zamorano, Yeray
dc.contributor.authorFernández Carnero, Josué
dc.contributor.authorSánchez Cuesta, Francisco José
dc.contributor.authorArroyo Ferrer, Aída
dc.contributor.authorVourvopoulos, Athanasios
dc.contributor.authorFigueiredo, Patricia
dc.contributor.authorSerrano, José Ignacio
dc.contributor.authorRomero Muñoz, Juan Pablo 
dc.date.accessioned2022-02-24T09:35:16Z
dc.date.available2022-02-24T09:35:16Z
dc.date.issued2021
dc.identifier.issn2076-3425spa
dc.identifier.urihttp://hdl.handle.net/10641/2861
dc.description.abstractPain is an under-reported but prevalent symptom in Parkinson’s Disease (PD), impacting patients’ quality of life. Both pain and PD conditions cause cortical excitability reduction and non-invasive brain stimulation. Mental representation techniques are thought to be able to counteract it, also resulting effectively in chronic pain conditions. We aim to conduct two independent studies in order to evaluate the efficacy of transcranial direct current stimulation (tDCS) and mental representation protocol in the management of pain in PD patients during the ON state: (1) tDCS over the Primary Motor Cortex (M1); and (2) Action Observation (AO) and Motor Imagery (MI) training through a Brain-Computer Interface (BCI) using Virtual Reality (AO + MI-BCI). Both studies will include 32 subjects in a longitudinal prospective parallel randomized controlled trial design under different blinding conditions. The main outcomes will be score changes in King’s Parkinson’s Disease Pain Scale, Brief Pain Inventory, Temporal Summation, Conditioned Pain Modulation, and Pain Pressure Threshold. Assessment will be performed pre-intervention, post-intervention, and 15 days post-intervention, in both ON and OFF states.spa
dc.language.isoengspa
dc.publisherBrain Sciencesspa
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 España*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/*
dc.subjectParkinson’s Diseasespa
dc.subjectTranscranial direct current stimulationspa
dc.subjectAction observationspa
dc.subjectMotor imageryspa
dc.subjectPainspa
dc.titleNew Approaches Based on Non-Invasive Brain Stimulation and Mental Representation Techniques Targeting Pain in Parkinson’s Disease Patients: Two Study Protocols for Two Randomized Controlled Trials.spa
dc.typejournal articlespa
dc.type.hasVersionAMspa
dc.rights.accessRightsopen accessspa
dc.description.extent453 KBspa
dc.identifier.doi10.3390/brainsci11010065spa
dc.relation.publisherversionhttps://www.mdpi.com/2076-3425/11/1/65spa


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Atribución-NoComercial-SinDerivadas 3.0 España
Except where otherwise noted, this item's license is described as Atribución-NoComercial-SinDerivadas 3.0 España