Browsing by Author "Coronado, Pluvio J."
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Item Development and psychometric properties of the human papillomavirus‑quality of life (HPV‑QoL) questionnaire to assess the impact of HPV on women health‑related‑quality‑of‑life.(Archives of Gynecology and Obstetrics, 2022) Coronado, Pluvio J.; González‑Granados, Carmen; Ramírez‑Mena, Mar; Calvo, Javier; Fasero Laiz, María; Bellón, Mónica; García‑Santos, Javier F.; Rejas‑Gutiérrez, JavierPurpose The HPV-Quality-of-Life (HPV-QoL) questionnaire was developed to determine the impact of Human-Papillomavirus (HPV) infection and related interventions on women health-related quality-of-life. This study provides the development and preliminary psychometric properties of a novel HPV-QoL questionnaire for adult women with HPV. Methods After reviewing literature and cognitive debriefing interviews in women who had experienced HPV-related conditions, instrument items and domains were developed. A draft questionnaire was pilot tested for comprehension and ease of completion. Psychometric evaluation of the final HPV-QoL scale was conducted in a psychometric study including 252 adult women derived to our centre by a positive HPV test in the cervical cancer screening program and/or presenting genital warts. Results The present study reveals that the HPV-QoL questionnaire, structured in four domains: general well-being [including psychological well-being and social well-being subdomains], health, contagiousness and sexuality, showed good metric properties of feasibility irrespective of age or educational level, and time to administer was less than 5 min. Internal consistency and temporal stability (reliability) showed values above the acceptable standards. The instrument showed its concurrent validity by means of a significant correlation with mental and sexual existing instruments; GHQ-12 and FSFI questionnaires, respectively, and also known groups validity showing significant differences among the subgroups regarding either sexual dysfunction or mental deterioration. Conclusion This study provides an HPV-QoL questionnaire with an innovative patient-reported outcomes specific measurement tool to assess HRQoL in women with HPV infection. The present study suggests this questionnaire has satisfactory psychometric properties, including validity and reliability. Results support the use of the HPV-QoL questionnaire as a HRQoL measurement instrument for daily medical practice and clinical research.Item Health-related quality of life and resilience in peri- and postmenopausal women during Covid-19 confinement.(Maturitas, 2021) Coronado, Pluvio J.; Fasero Laiz, María; Otero, Borja; Sánchez, Sonia; De la Viuda, Esther; Ramírez Polo, Isabel; Llaneza, Plácido; Mendoza, Nicolás; Baquedano, LauraObjective To assess the impact of confinement due to the coronavirus (Covid-19) pandemic on health-related quality of life (HRQoL) and resilience in peri- and postmenopausal women. Material and Methods We used an online questionnaire which was sent between April 30th and May 13th, 2020 to women aged 40–70 years who were peri- or postmenopausal according to STRAW criteria. We used the 16-item Cervantes short-form scale (Cervantes-SF) to measure HRQoL, and the 14-item Wagnild and Young Resilience Scale (RS-14) to measure resilience. High scores on the Cervantes-SF indicate low HRQoL and high scores on the RS-14 indicate high levels of resilience. Covid-19 status, sociodemographic descriptors, and lifestyle variables were also evaluated. Results We included 2430 peri- and postmenopausal women with valid questionnaires. All items of the Cervantes-SF were completed in 2151 cases, whilst the RS-14 was completed in 2413 cases. There was a negative correlation between scores on the Cervantes-SF and RS-14 scales (Rho -0.350; p < 0.0001). Multiple linear regression analysis revealed a statistically significant association between Cervantes-SF scores and living with others (β-coefficient -10.2; p < 0.001), use of antidepressants (β 9.3; p < 0.001), physical activity (β -8.6; p < 0.001) and sexual activity (β -2.7; p < 0.001). Resilience was associated with the use of antidepressants (β -5.9; p < 0.001), physical activity (β 3.2; p < 0.001) and sexual activity (β 1.7; p = 0.005). According to the multivariate analysis, there were no associations between either Covid-19 or menopausal status and HRQoL or resilience scores. Conclusions During the period of mandatory Covid-19 confinement, peri- and postmenopausal women who engaged in physical and sexual activity had higher HRQoL and higher levels of resilience, whilst women who were using antidepressants had lower HRQoL and lower levels of resilience. HRQoL was greater in women who lived with others.Item Predictive and criterion validity of the Cervantes-SF menopause quality of life questionnaire.(Menopause, 2021) Coronado, Pluvio J.; Monroy, Manuel; Fasero Laiz, María; Baquedano, Laura; Mendoza, Nicolás; Llaneza, Plácido; Rejas, Javier; Ruiz, Miguel A.Item What do Spanish men know about menopause?(Menopause, 2020) Fasero Laiz, María; Baquedano Mainar, Laura; Ruiz Campo, Leyre; Varillas Delgado, David; Coronado, Pluvio J.Objective: The aim of the study is to evaluate the knowledge that men have about menopause and to analyze whether sociodemographic aspects influence in this knowledge. Methods: 560 consecutive surveys were collected during 2019. The surveys were completed anonymously, voluntarily and without incentives by men. A maximum score of 45 points was considered for the knowledge analysis. Results: The mean age was 49.13 ± 11.1 years. The most frequent source of information to obtain knowledge about menopause were friends (61.4%). The mean of the questionnaire score was 20.69 ± 6.1. The most frequent symptoms associated with menopause were hot flashes and vaginal dryness (93.7%; 48%) and the best-known treatment to improve vaginal health was lubricants at 69.5%. The most common treatment men know for improving menopause symptoms was menopause hormone treatment; however, 27.9% of men think there is no treatment for menopause. Differences between ages in numbers and grades were found (p=0.032). The scores by levels of study showed statistically differences (primary school, high school, professional training and university education (men with a higher level of education had significantly more knowledge) (p=0.013). Differences were showed in men who obtained information from health staff with respect to other sources (p<0.001). Conclusions: The knowledge in men in this sample is limited. Differences between ages, level of education and sources of information were found. No differences were found between public and private hospitals. The teaching of this knowledge should be carried out by trained personnel, preferably health staff.Item Women with low quality of life by cervantes-short form scale choose menopausal hormone therapy.(European Journal of Obstetrics & Gynecology and Reproductive Biology, 2020) Fasero Laiz, María; Hernández, Antonio; Varillas Delgado, David; Coronado, Pluvio J.Objectives The aim of the study is to assess whether women who choose to use menopausal hormone therapy (MHT) have lower quality of life (QoL) than those who do not initiate it using Cervantes short form scale (C-SF), and analyze sociodemographic factors associated with lower QoL in women. Study design A cross-sectional descriptive observational study was made in four hundred and eighty women with climacteric symptoms. Results Mean age was 51.1 years. Two hundred and sixty-one women (54.3 %) started MHT. The sample´s global mean in C-SF score was 51.3 ± 13.9. Women who choose to use MHT have higher score in C-SF (lower QoL) than women who reject it (58.7 ± 15.9 vs 46.7 ± 12.8; p < 0.001). We found higher score in women with early menopause (53.7 ± 15.9 vs 49.7 ± 13.1; p = 0.037); with no obesity (<30 vs >30 BMI) (52.8 ± 13.5 vs 41.0 ± 8.2; p = 0.002); with previous malignancies (56.2 ± 18.2 vs 50.2 ± 13.5; p = 0.020) and without sexual activity (58.0 ± 25.4 vs 50.4 ± 13.1; p = 0.009. No differences were found in C-SF score with respect to tobacco habits or physical activity. In the multivariate analysis, the variable independently associated to lower QoL by C-SF (high score) was to be a woman who want to initiate MHT (p = 0.004). Conclusions Women who choose to use MHT due to menopausal symptoms have lower quality of life measured by C-SF scale. Women with early menopause, with no obesity (<30 BMI), without sexual activity and with previous malignances have lower quality of life measured by C-SF scale. Women with early menopause have more psychic symptoms like nervousness, fatigue and sleep complaints by C-SF scale than women with natural menopause.