Acute p-synephrine ingestion increases whole-body fat oxidation during 1-h of cycling at Fatmax.
dc.contributor.author | Gutiérrez Hellín, Jorge | |
dc.contributor.author | Ruiz Moreno, Carlos | |
dc.contributor.author | Del Coso, Juan | |
dc.date.accessioned | 2020-07-02T11:15:23Z | |
dc.date.available | 2020-07-02T11:15:23Z | |
dc.date.issued | 2019 | |
dc.description.abstract | Purpose p-Synephrine, the principal alkaloid of bitter orange (Citrus aurantium), is widely used in dietary supplements for weight loss due to its purported effect of increasing fat oxidation. However, there is a paucity of scientific information about its effectiveness in enhancing fat oxidation during exercise. The aim of this investigation was to determine the effect of an acute dose of p-synephrine on substrate oxidation during prolonged and constant intensity exercise. Methods In a double-blind and randomized experiment, 14 healthy subjects performed two acute experimental trials after ingesting either p-synephrine (3 mg kg−1) or a placebo (cellulose). Energy expenditure and fat oxidation rates were continuously measured by indirect calorimetry during 1 h of continuous cycling at Fatmax, the intensity that induces maximal fat oxidation rate. Results In comparison to the placebo, energy expenditure during 1 h of cycling remained unchanged with p-synephrine (698 ± 129 vs. 686 ± 123 kcal, P = 0.08). However, p-synephrine increased whole-body fat oxidation (33.6 ± 10.4 vs. 37.3 ± 9.8 g, P < 0.01) while also reducing carbohydrate oxidation (99.5 ± 30.4 vs. 85.0 ± 28.4 g, P < 0.01). However, the magnitude of the shift on substrate oxidation induced by p-synephrine was small. Conclusion Acute ingestion of p-synephrine augments fat oxidation during prolonged and constant-intensity exercise. | spa |
dc.description.extent | 193 KB | spa |
dc.identifier.doi | 10.1007/s00394-019-02101-6 | spa |
dc.identifier.issn | 1436-6207 | spa |
dc.identifier.uri | http://hdl.handle.net/10641/1943 | |
dc.language.iso | eng | spa |
dc.publisher | European Journal of Nutrition | spa |
dc.relation.publisherversion | https://link.springer.com/article/10.1007/s00394-019-02101-6 | spa |
dc.rights | Atribución-NoComercial-SinDerivadas 3.0 España | * |
dc.rights.accessRights | open access | spa |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | * |
dc.subject | Nutrition supplement | spa |
dc.subject | Exercise | spa |
dc.subject | Citrus aurantium | spa |
dc.subject | Bitter orange | spa |
dc.subject | Maximal fat oxidation | spa |
dc.title | Acute p-synephrine ingestion increases whole-body fat oxidation during 1-h of cycling at Fatmax. | spa |
dc.type | journal article | spa |
dc.type.hasVersion | SMUR | spa |
dspace.entity.type | Publication | |
relation.isAuthorOfPublication | 1cccb91f-5305-4dcf-aa87-7e567976cc29 | |
relation.isAuthorOfPublication.latestForDiscovery | 1cccb91f-5305-4dcf-aa87-7e567976cc29 |
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