Moncada, IgnacioKrishnappa, PramodAscencios, JulmarLopez, InigoMartínez Salamanca, Juan Ignacio2021-11-052021-11-0520200955-9930http://hdl.handle.net/10641/2587The aim of this study was to study the clinical effectiveness of a structured home modeling (HM) protocol in Peyronie’s 9 disease (PD) patients who have residual curvature up to 45° after inflatable penile prosthesis (PP) placement. A total of 92 10 patients with PD and coexistent refractory erectile dysfunction received inflatable PP. If residual curvature after manual 11 modeling (MM) was more than 45°, incision–grafting was performed. If curvature was <45° after MM, patients were 12 instructed to perform HM daily for 6 months, after 4 weeks from PP implantation. The mean preoperative penile curvature 13 was 39.4 ± 5.7° (30–60). Sixteen (17.4%) patients required incision–grafting and the remaining 76(82.6%) patients followed 14 HM protocol. The mean postoperative residual curvature after MM was 29.7 ± 3.2° (5–50). Sixty-five (85.5%) patients who 15 underwent HM had 10° or less residual curvature after 3 months and 72 (94.7%) patients had 10° or less residual curvature 16 after 6 months. Seventy (92.1%) patients responded as satisfied or very satisfied on the questionnaire with the outcome after 17 6 months. HM of the penis over Inflatable PP may straighten the penis without the need for an additional surgical maneuver 18 in vast majority of the PD patients having residual curvature of <45°.engAtribución-NoComercial-SinDerivadas 3.0 Españahttp://creativecommons.org/licenses/by-nc-nd/3.0/es/journal articleopen access10.1038/s41443-020-0325-6