Romero Muñoz, Juan PabloSánchez Cuesta, Francisco JoséDoctorado en Biotecnología, Medicina y Ciencias Biosanitarias.2024-07-312024-07-312024https://hdl.handle.net/10641/5184Nota: fecha de lectura 15/07/2024Introducción: La Organización Mundial de la Salud (OMS) definió el accidente cerebrovascular (ACV) como una alteración cerebral vascular que produce síntomas neurológicos de inicio brusco, con duración de más de 24 horas. Representa una de las principales causas de discapacidad y muerte en España y a nivel mundial. Después de un semestre del evento cerebro vascular, más del 60% de los participantes no pueden realizar tareas esenciales de la vida diaria debido a problemas motores entre los cuales son muy significativos aquellos que afectan la mano.Introduction: The World Health Organization (WHO) defines stroke as a cerebrovascular alteration resulting in sudden onset neurological symptoms lasting over 24 hours. It stands as a major cause of disability and death both in Spain and globally. Following a six-month period post-stroke, over 60% of participants experience difficulties performing essential daily tasks due to motor impairments, particularly those affecting the hand. Various techniques complement conventional rehabilitation, focusing on enhancing cerebral excitability to potentiate its effects. Non-invasive exogenous and endogenous cerebral neuromodulation techniques are among these strategies. Repetitive Transcranial Magnetic Stimulation (rTMS) is an exogenous neuromodulation technique successfully tested in stroke motor rehabilitation. Additionally, neurofeedback and motor imagery represent endogenous neuromodulation techniques, also displaying promising outcomes in improving aspects such as strength, dexterity, and functionality of the affected upper limb. However, few studies have investigated the combined effects of endogenous and exogenous strategies in stroke rehabilitation.engAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/doctoral thesisopen access