Llamas-Velasco, SaraRomero Ferreiro, María CarmenGonzález Fuertes, ÁlvaroGarcía Tell, PaolaBlanco Palmero, Víctor AntonioMartín-Jiménez, PalomaPérez Martínez, David AndrésMéndez Guerrero, Antonio2024-12-032024-12-032024Llamas-Velasco, S., Romero Ferreiro, C., González Fuertes, Á., et al. (2023). Home calligraphic exercises as manual dexterity training in patients with Parkinson’s disease: a pilot feasibility study. Disability and Rehabilitation, Vol. Núm. 5, pp. 870–874.0963-8288https://hdl.handle.net/10641/5508Purpose To assess the feasibility and effects on manual dexterity and the quality of life (QoL) of a 12-week home calligraphic training program in patients with Parkinson’s disease (PD). Methods A pilot study with participants recruited from the Movement Disorders consultation at the Hospital 12 de Octubre (Madrid). The main outcome, manual dexterity, was assessed using the Purdue Pegboard Test (PPT). Secondary outcomes included clinical rating scales that contemplate aspects related to manual dexterity (DextQ-24, UPDRSII, UPDRSIII), and QoL (PDQ-39 and EuroQoL-5D). Results Thirty PD patients (57% males) with a mean age of 66.11 (9.76) years and 93% adherence rate. The PPT scores improved significantly (p < 0.0001) from T0 (start of the study) to T1 (after 24 weeks). No statistically significant change was found in DextQ-24, UPDRS-II and UPDRS-III, but a clear improvement was observed in the QoL measurement: EuroQoL-5D (p < 0.0001), PDQ-39 (p < 0.0001) and modified PDQ-39 (p = 0.022). Conclusions This is the first study to demonstrate the feasibility and improvement in hand dexterity assessed by the PPT for patients diagnosed with PD after a 12-week home calligraphic training program. A significant improvement was noted in the QoL measurements, such as the PDQ-39, modified PDQ-39, and EuroQoL-5D.engAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/Parkinson’s diseaseCalligraphic exercisesManual dexterityQuality of lifeDisabilityjournal articleembargoed access10.1080/09638288.2023.2181408