de Miguel, AránzazuAgejas Esteban, José ÁngelAgejas, José ÁngelOrón Semper, José VíctorOrón, José Víctor2025-12-192025-12-192025-07de Miguel, A, Agejas, J Á & Orón, J V 2025, 'Systematic and Narrative Review of the Mediating Role of Personal Relationships Between Mental Health and Nutrition', Nutrients, vol. 17, no. 14, 2318. https://doi.org/10.3390/nu171423182072-6643PubMedCentral: PMC12300011unpaywall: 10.3390/nu17142318https://hdl.handle.net/10641/6848Publisher Copyright: © 2025 by the authors.Background/Objectives: The complex relationship between nutrition and mental well-being has been widely documented, with empirical evidence supporting both the influence of dietary habits on psychological health and, conversely, the impact of mental state on food choices. However, a critical gap remains in understanding the mechanisms underlying this interaction. While previous literature have examined various biological and psychological mediators, limited attention has been given to the potential mediation role of interpersonal relationships in shaping this dynamic. This article seeks to address this theoretical gap by exploring how the quality of social interactions—both in their intentional dimension and in their lived experiential aspect—may function as a key mediator between nutrition and mental well-being. Methods: Methodologically, a combination of systematic review (PRISMA) and narrative review was employed, given that the findings of the systematic review alone are insufficient to formulate a hypothesis that requires interdisciplinary dialog in a still emerging and underexplored field. Results: The hypothesis we aim to propose is whether the quality of interpersonal relationships acts as a catalyst and enhancer of the effect of nutrients on mental health. Conclusions: This could open new avenues for the design of dietary interventions and mental well-being programs from a socially integrated approach.743585enghttp://creativecommons.org/licenses/by-nc-nd/4.0/dietinterpersonal relationshipsmediating effectmental healthnutritionwell-beingFood ScienceNutrition and DieteticsSDG 3 - Good Health and Well-beingYesyesreview articleopen access10.3390/nu17142318https://www.scopus.com/pages/publications/105011654877https://www.scopus.com/pages/publications/105011654877#tab=citedBy