Fasero Laíz, MaríaSanchez, M.Baquedano, L.Gippini, I.Fuentes, D.Navarro, C.Beltrán, E.Lilue, M.Porcel, I.Pingarrón, C.Herrero, M.Romero, P.Ortega, T.Carretero, E.Palacios, S.Mendoza, N.Coronado, P. J.2026-01-272026-01-272025-03Fasero, M, Sanchez, M, Baquedano, L, Gippini, I, Fuentes, D, Navarro, C, Beltrán, E, Lilue, M, Porcel, I, Pingarrón, C, Herrero, M, Romero, P, Ortega, T, Carretero, E, Palacios, S, Mendoza, N & Coronado, P J 2025, 'Management of menopausal hot flushes. Recommendations from the Spanish Menopause Society', European Journal of Obstetrics and Gynecology and Reproductive Biology: X, vol. 25, 100366. https://doi.org/10.1016/j.eurox.2025.1003662590-1613PubMedCentral: PMC11814524https://hdl.handle.net/10641/7519Publisher Copyright: © 2025 The AuthorsThis project aims to develop recommendations for treating vasomotor symptoms (VMS) based on the Cervantes short-form scale score (menopausal domain) using the best available evidence. A total of 166 studies were selected: 108 randomized controlled trials, 23 systematic reviews, 3 reviews, 3 meta-analyses, 11 case-control studies, 9 observational studies, and 12 transversal studies. To achieve this objective, a series of PICO (Patient, Intervention, Comparison, and Outcome) questions have been established for the treatment of VMS. We evaluate the quality of the scientific evidence and, with the findings, create a decision framework to treat hot flashes based on the Cervantes short-form scale score.1652219enghttp://creativecommons.org/licenses/by-nc-nd/4.0/Climacteric symptomsFlushingHot flashesHot flushesMenopausal symptomsMenopauseVasomotor symptoms, night sweatsReproductive MedicineObstetrics and GynecologyYesyesreview articleopen access10.1016/j.eurox.2025.100366https://www.scopus.com/pages/publications/85216202682https://www.scopus.com/pages/publications/85216202682#tab=citedBy