NUTRICIÓN HUMANA Y DIETÉTICA
Permanent URI for this collectionhttps://hdl.handle.net/10641/3174
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Browsing NUTRICIÓN HUMANA Y DIETÉTICA by Keyword "Antioxidant properties"
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Item Red Quinoa hydrolysates with antioxidant bioactive properties on oxidative stress-induced Saccharomyces cerevisiae.(LWT. Food Science and Technology, 2023) López Moreno, Miguel; Sabater-Muñoz, Beatriz; Iglesias López, María Teresa; Miguel-Castro, Marta; Garcés Rimón, MartaQuinoa (Chenopodium quinoa Willd) is a pseudo-cereal of great interest for its nutritional value. Specifically, enzymatic hydrolysis of quinoa proteins has shown several biological activities. The purpose of this study was to investigate the influence of enzymatic hydrolysis on antioxidant by the oxygen radical absorbance capacity (ORAC) method and sensory properties of white, red and black quinoa varieties, and to evaluate the in vivo antioxidant capacity of the most promising quinoa hydrolysate using Saccharomyces cerevisiae BY4741 as an experimental model. The results showed a hydrolysate from red quinoa seeds with a promising sensory profile and antioxidant activity. Although more studies in experimental models and human trials will be necessary to corroborate the antioxidant effect and the mechanisms of action involved, the results obtained may allow the development of new plant-based foods with antioxidant properties scientifically supported and useful in the prevention and/or the treatment of pathologies related to oxidative stress.Item Red Quinoa Hydrolysates with Antioxidant Properties Improve Cardiovascular Health in Spontaneously Hypertensive Rats.(Antioxidants, 2023) López Moreno, Miguel; Jiménez-Moreno, Estefanía; Márquez Gallego, Antonio; Vera Pasamontes, Gema; Uranga Ocio, José Antonio; Garcés Rimón, Marta; Miguel-Castro, MartaIn recent years, quinoa has been postulated as an emerging crop for the production of functional foods. Quinoa has been used to obtain plant protein hydrolysates with in vitro biological activity. The aim of the present study was to evaluate the beneficial effect of red quinoa hydrolysate (QrH) on oxidative stress and cardiovascular health in an in vivo experimental model of hypertension (HTN) in the spontaneously hypertensive rat (SHR). The oral administration of QrH at 1000 mg/kg/day (QrHH) showed a significant reduction in SBP from baseline (−9.8 ± 4.5 mm Hg; p < 0.05) in SHR. The mechanical stimulation thresholds did not change during the study QrH groups, whereas in the case of SHR control and SHR vitamin C, a significant reduction was observed (p < 0.05). The SHR QrHH exhibited higher antioxidant capacity in the kidney than the other experimental groups (p < 0.05). The SHR QrHH group showed an increase in reduced glutathione levels in the liver compared to the SHR control group (p < 0.05). In relation to lipid peroxidation, SHR QrHH exhibited a significant decrease in plasma, kidney and heart malondialdehyde (MDA) values compared to the SHR control group (p < 0.05). The results obtained revealed the in vivo antioxidant effect of QrH and its ability to ameliorate HTN and its associated complications.