Dichotomous colorectal cancer behaviour.
dc.contributor.author | Aljama, Sara | |
dc.contributor.author | Pérez Lago, Estela | |
dc.contributor.author | Zafra Amorós, Olga | |
dc.contributor.author | Sierra Isturiz, Javier | |
dc.contributor.author | Simón, Diana | |
dc.contributor.author | Santos Tejedor, Cruz | |
dc.contributor.author | Rodriguez Pascual, Jesus | |
dc.contributor.author | García Romero, Noemí | |
dc.date.accessioned | 2023-12-11T09:26:14Z | |
dc.date.available | 2023-12-11T09:26:14Z | |
dc.date.issued | 2023 | |
dc.description.abstract | Colorectal cancer (CRC) is the third most common malignant tumor and one of the deadliest cancers. At molecular level, CRC is a heterogeneous disease that could be divided in four Consensus Molecular Subtypes. Given the differences in the disease due to its anatomical location (proximal and distal colon), another classification should be considered. Here, we review the current knowledge on CRC dichotomic´s behaviour based on two different entities; right and left-sided tumors, their impact on clinical trial data, microbiota spatial composition and the interaction with the nervous system. We discuss recent advances in understanding how the spatial tumor heterogeneity influences the tumor growth, progression, and responses to current therapies | spa |
dc.description.extent | 3748 KB | spa |
dc.identifier.doi | 10.1016/j.critrevonc.2023.104067 | spa |
dc.identifier.issn | 1040-8428 | spa |
dc.identifier.uri | https://hdl.handle.net/10641/3554 | |
dc.language.iso | eng | spa |
dc.publisher | Critical Reviews in Oncology/Hematology | spa |
dc.relation.publisherversion | https://www.sciencedirect.com/science/article/pii/S1040842823001555?via%3Dihub | spa |
dc.rights | Atribución-NoComercial-SinDerivadas 3.0 España | * |
dc.rights.accessRights | open access | spa |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | * |
dc.subject | Colorectal cancer | spa |
dc.subject | Right side | spa |
dc.subject | Left side | spa |
dc.subject | Microbiota | spa |
dc.subject | Clinical trials | spa |
dc.title | Dichotomous colorectal cancer behaviour. | spa |
dc.type | journal article | spa |
dc.type.hasVersion | AM | spa |
dspace.entity.type | Publication | |
relation.isAuthorOfPublication | 474545c4-1034-43c9-b4c1-fa938984f41d | |
relation.isAuthorOfPublication | be7339a7-8121-44b8-bccb-eeef5135428c | |
relation.isAuthorOfPublication | fe393f35-cc58-4793-8d1f-469e128f573a | |
relation.isAuthorOfPublication.latestForDiscovery | 474545c4-1034-43c9-b4c1-fa938984f41d |
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