Functional independence, frailty and perceived quality of life in patients who developed delirium during ICU stay: a prospective cohort study.
dc.contributor.author | Lobo Valbuena, Beatriz | |
dc.contributor.author | Molina, Rosario | |
dc.contributor.author | Castañeda-Vozmediano, Raul | |
dc.contributor.author | Lopez de la Oliva Calvo, Leire | |
dc.contributor.author | Abella, Ana | |
dc.contributor.author | Garcia‑Arias, María‑Mercedes | |
dc.contributor.author | Salinas Gabiña, Irene | |
dc.contributor.author | Gordo Vidal, Federico | |
dc.date.accessioned | 2024-02-12T20:25:55Z | |
dc.date.available | 2024-02-12T20:25:55Z | |
dc.date.issued | 2023 | |
dc.description.abstract | Background Survivors of critical illness are frequently left with a long-lasting disability. We hypothesised that patients who developed delirium during ICU stay, compared with patients who did not, would have worse health-related quality of life following a critical illness. Methods Prospective longitudinal observational and analytical study assessing functional independence, frailty and perceived quality of life measured with the Barthel Index, the Clinical Frailty Scale, and the SF-36, comparing patients who developed delirium during ICU stay and patients who did not. The questionnaires were used at different times during the follow-up (upon ICU admission, at ICU discharge, at hospital discharge and 2 years after hospital discharge). Results In a cohort of 1462 patients, we matched 93 patients who developed delirium (delirium group) with 93 patients who did not develop delirium (no-delirium group). Of 156 completed questionnaires (84.7%), we observed that (a) in each of the two groups of patients, the scores related to functional independence (Barthel Index) and frailty (Clinical Frailty Scale) tended to improve over time (p < 0.001), being consistently less favourable in the delirium group compared to the no-delirium group (p < 0.001); (b) the patients who developed delirium also presented lower scores on the SF-36 scale, these differences being statistically significant, and therefore evidencing a worse quality of life, with impact on both the psychological and social spheres (p < 0.001). Conclusions Patients who developed delirium had significantly lower scores 2 years after hospital discharge on the three used questionnaires, displaying a clear negative impact on the physical, psychological, and social dimensions. The study's results reinforce the need to support and strengthen the care of ICU survivors. | spa |
dc.description.extent | 1444 KB | spa |
dc.identifier.doi | 10.1186/s40001-023-01530-8 | spa |
dc.identifier.issn | 2047-783X | spa |
dc.identifier.uri | https://hdl.handle.net/10641/3965 | |
dc.language.iso | eng | spa |
dc.publisher | European Journal of Medical Research | spa |
dc.relation.publisherversion | https://eurjmedres.biomedcentral.com/articles/10.1186/s40001-023-01530-8 | spa |
dc.rights | Atribución-NoComercial-SinDerivadas 3.0 España | * |
dc.rights.accessRights | open access | spa |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | * |
dc.subject | Activities of daily living | spa |
dc.subject | Critical care | spa |
dc.subject | Delirium | spa |
dc.subject | Health-related quality of life | spa |
dc.subject | Post-intensive care syndrome | spa |
dc.title | Functional independence, frailty and perceived quality of life in patients who developed delirium during ICU stay: a prospective cohort study. | spa |
dc.type | journal article | spa |
dc.type.hasVersion | AM | spa |
dspace.entity.type | Publication | |
relation.isAuthorOfPublication | f41b7b93-d6dd-4126-acb4-7088a89be2f4 | |
relation.isAuthorOfPublication | bcd97a00-84cb-4bd4-aa64-cae516e265ac | |
relation.isAuthorOfPublication.latestForDiscovery | f41b7b93-d6dd-4126-acb4-7088a89be2f4 |
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