PSICOLOGÍA
Permanent URI for this collectionhttps://hdl.handle.net/10641/1441
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Browsing PSICOLOGÍA by Keyword "Anxiety"
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Item Building Resilience with Aerobic Exercise: Role of FKBP5.(Current Neuropharmacology, 2021) Sampedro Piquero, P.; Moreno Fernández, Román DaríoBoth preclinical and clinical studies have pointed that aerobic exercise, at moderate doses, is beneficial at all stages of life by promoting a range of physiological and neuroplastic adaptations that reduce the anxiety response. Previous research about this topic have repeatedly described how the regular practice of aerobic exercise induces a positive regulation of neuroplasticity and neurogenesis-related genes, as well as a better control of the HPA axis function. However, limited progress has been carried out in the integration of neuroendocrine and neuroplastic changes, as well as in introducing new factors to understand how aerobic exercise can promote resilience to future stressful conditions. Resilience is defined as the ability to adapt to stress while maintaining healthy mental and physical performance. Consistent findings point to an important role of FKBP5, the gene expressing FK506-binding protein 51 (FKBP51), as a strong inhibitor of the glucocorticoid receptor (GR), and thus, an important regulator of the stress response. We propose that aerobic exercise could contribute to modulate FKBP5 activity acting as a potential therapeutic approach for mood disorders. In this sense, aerobic exercise is well known for increasing the growth factor BDNF, which by downstream pathways could affect the FKBP5 activity. Therefore, our manuscript has the aim of analyzing how FKBP5 could constitute a promising target of aerobic exercise promoting resilient-related phenotypes.Item Perinatal Mental Health during the COVID-19 Pandemic: A Longitudinal Study.(Clínica y Salud, 2023) Chaves Vélez, Covadonga; Mezei, Ioana; Marchena Giráldez, Carlos Alberto; Duque, AlmudenaFew studies have shown the psychological impact of the COVID-19 pandemic on new mothers’ health, but the long-term consequences of the crisis are yet unknown. This study aimed at evaluating the changes experienced in perinatal mental health 6 months after the start of the COVID-19 pandemic in Spain. Women (n = 176, average age = 33.80) were recruited during the pandemic. Participants completed the Edinburgh Postnatal Depression Scale, the Satisfaction With Life Scale and Positive, and the Negative Affect Schedule. Results showed a decrease in depressive symptoms, t(174) = 2.58, p = .01, d = 0.02, whereas anxiety symptoms remained high, t(174) = 1.31, p = .19. In terms of psychological well-being, the results showed a decrease in life satisfaction, t(175) = 2.58, p = .011, d = 0.16, and negative affect, t(175) = 3.15, p = .002, d = 0.26, and an increase in positive affect, t(175) = -4.45, p < .001, d = 0.35. This study is expected to shed light on the design of future interventions aimed at the prevention of symptoms and to enhance life satisfaction during the perinatal stage.